The Isleta Pueblo Historic District is listed on the National Register of Historic Places. The pueblo was built on a knife-shaped reef of lava running across an ancient Rio Grande channel. It is adjacent to and east of the main section of Laguna Pueblo. Pueblo of Isleta is located in the Middle Rio Grande Valley, 13 miles (21 km) south of Albuquerque. Its people are a federally recognized tribe. The Southern Tiwa name of the pueblo is Shiewhibak (Shee-eh-whíb-bak) meaning 'a knife laid on the ground to play whib', a traditional footrace. Pueblo of Isleta ( Southern Tiwa: Shiewhibak, Western Keres: Dîiw'a'ane Navajo: Naatoohó ) is an unincorporated community and Tanoan pueblo in Bernalillo County, New Mexico, United States, originally established in the c. Isleta Lakes Recreational Complex and tribal casino.

Adobe San Agustín de la Isleta Mission, with wooden Gothic Revival elements introduced by Padre Anton Docher, shown in 1925.